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FoxO3A Polyclonal Antibody, 100ul[BT-AP03334] Funnels This gene has been implicated

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FoxO3A Polyclonal Antibody, 100ul[BT-AP03334] Funnels This gene has been implicatedFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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Description

This gene has been implicated in multiple neurological disorders

Also catalyzes actin polymerization in the absence of Arp2/3

Three types of actins

Mutations in this gene are associated with mitochondrial complex I deficiency

potentially participating in the degradation of type II collagen-rich cartilage matrix

FoxO3A Polyclonal Antibody, 100ul[BT-AP03334] Funnels This gene has been implicatedFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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