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Romidepsin Catalog No.:M8157-10 GluR1 trafficking

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Romidepsin Catalog No.:M8157-10 GluR1 traffickingRomidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia induced angiogenesis and depletes several heat shock

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Description

GluR1 trafficking

269(7):5241-8

Free Radic Res

[Pharmacokinetics and disposition of triptonide in rats]

Molecular Weight: 378

Romidepsin Catalog No.:M8157-10 GluR1 traffickingRomidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia induced angiogenesis and depletes several heat shock

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