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OSI-906 Size:10mg solid InChi: InChI=1S/C42H70O11

SKU: 97796640028

4.2
EUR126.00 EUR170.00

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OSI-906 Size:10mg solid InChi: InChI=1S/C42H70O11OSI 906, is a n orally bioavailable small molecule inhibitor of the insulin like growth factor 1 receptor (IGF 1R) with potential antineoplastic activity. OSI 906 selectively inhibits IGF 1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR 1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. Product

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Description

InChi: InChI=1S/C42H70O11

PRI-724 treatment reduces the fibrosis induced by CCl4 or BDL

PubMed PMID: 17889719

AEE788 inhibits the growth of Daoy

872365-14-5

OSI-906 Size:10mg solid InChi: InChI=1S/C42H70O11OSI 906, is a n orally bioavailable small molecule inhibitor of the insulin like growth factor 1 receptor (IGF 1R) with potential antineoplastic activity. OSI 906 selectively inhibits IGF 1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR 1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. Product

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