4SC-202 - HDAC/LSD1 Dual Inhibitor. CAS# 1186222-89-8 size:2 mg solid InChi: InChI=1S/C16H14N4O/c1-10(2)13-14(11-6-4-3-5-7-11)19-15-12(8-17)9-18-20(15)16(13)21/h3-7
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4SC-202 - HDAC/LSD1 Dual Inhibitor. CAS# 1186222-89-8 size:2 mg solid InChi: InChI=1S/C16H14N4O/c1-10(2)13-14(11-6-4-3-5-7-11)19-15-12(8-17)9-18-20(15)16(13)21/h3-74SC 202, CAS No. 1186222 89 8, is a potent, selective and orally bioavailable HDAC LSD1 dual Inhibitor. It inhibits class I HDAC with IC50 of 1. 20M, 1. 12 M, and 0. 57M for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). 4SC 202 has very high selectivity over ClassIIa IIb III HDACs. In HeLa cells, it induces hyperacetylation of histone H3 with EC50 of 1. 1 M. It induces a G2 M
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