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Pixantrone (dimaleate) atran etexilate mesylate Inhibition of TNKS1/2 poly(ADP-ribosyl)ation activity

Pixantrone (dimaleate) atran etexilate mesylate Inhibition of TNKS1/2 poly(ADP-ribosyl)ation activity

Name: Pixantrone (dimaleate) atran etexilate mesylate Inhibition of TNKS1/2 poly(ADP-ribosyl)ation activity
Brand: trulybuild.in
SKU: 93305117007
Price: 80.00 USD
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SKU: 93305117007

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Pixantrone (dimaleate) atran etexilate mesylate Inhibition of TNKS1/2 poly(ADP-ribosyl)ation activityPixantrone is a synthetic, noncardiotoxic aza anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non Hodgkin lymphoma (aNHL). Product information CAS Number:

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Description

Inhibition of TNKS1/2 poly(ADP-ribosyl)ation activity by JW55 led to stabilization of AXIN2

an antianaemic drug candidate

InChi: InChI=1S/C25H24N8O7S2

CAS Number: 2068-78-2

InChiKey: UHDOJINBFLDQJM-UHFFFAOYSA-N

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