Bosutinib - CAS# 380843-75-4 287 Neurogastroenterol Motil

Neurogastroenterol Motil

in immune-competent BALB/c mice bearing syngeneic A20 lymphoma tumors

Smiles: CC1=C(C=C2SC(=O)N(C3C=CC=CC=3)C2=O)C=C(C)N1C1=CN=CC=C1

Formula: C30H29N5O6S2

CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@]12C)=C/C=C1/C[C@@H](O)CCC/1=C

Bosutinib - CAS# 380843-75-4 287 Neurogastroenterol MotilBosutinib, also known as SKI 606, is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Unlike imatinib, bosutinib inhibits the autophosphorylation of both Abl and Src kinases, resulting in inhibition of cell growth and apoptosis. Because of the dual mechanism of action, this agent may have activity in resistant CML disease, other myeloid malignancies and solid