![Lasmiditan Catalog No.:M10338-10 Smiles: CC1(C)[C@@H]2[C@@H](O)C[C@]3(C)[C@H](C[C@@H](O)[C@@H]4[C@H](CC[C@@]34C)[C@@](C)(O)CCC=C(C)C)[C@@]2(C)CC[C@@H]1O](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M10338_1621561719.gif?v=1621561721)
Lasmiditan Catalog No.:M10338-10 Smiles: CC1(C)[C@@H]2[C@@H](O)C[C@]3(C)[C@H](C[C@@H](O)[C@@H]4[C@H](CC[C@@]34C)[C@@](C)(O)CCC=C(C)C)[C@@]2(C)CC[C@@H]1O
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Lasmiditan Catalog No.:M10338-10 Smiles: CC1(C)[C@@H]2[C@@H](O)C[C@]3(C)[C@H](C[C@@H](O)[C@@H]4[C@H](CC[C@@]34C)[C@@](C)(O)CCC=C(C)C)[C@@]2(C)CC[C@@H]1OLasmiditan, also known as COL 144 and LY573144, is a novel, centrally acting, highly selective 5 HT(1F) receptor agonist (K1=2. 21 M) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof of concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2 hour placebo subtracted headache response of 28. 8%, though with frequent reports of dizziness, paresthesias, and vertigo.
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