Ifosfamide - CAS# 3778-73-2 anthine SB203580 also inhibits the activity

SB203580 also inhibits the activity of PDK1 in a dose-dependent manner with an IC50 in the 3–10 μm range

BM blue dihydrochloride

which is significantly lower than that of 3-AP (Triapine

Solubility: DMSO : 250 mg/mL (853

Thienopyridone drugs are selective activators of AMP-activated protein kinase β1-containing complexes

Ifosfamide - CAS# 3778-73-2 anthine SB203580 also inhibits the activityIfosfamide is a synthetic analogue of the nitrogen mustard cyclophosphamide with antineoplastic activity. Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. This agent is a prodrug that must be activated through hydroxylation by hepatic microsomal enzymes. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Product information CAS Number: 3778 73 2