Zosuquidar trihydrochloride - CAS# 167465-36-3 Size:Solid 2 mg ARRY-520 had low nanomolar antiproliferative

ARRY-520 had low nanomolar antiproliferative activity in tumor cell lines and specifically inhibits KSP (kinesin-5 or Eg5)

whereas SBE7-β-CD exhibits strong solubilizing effects over a wide concentration range

which represents a new structural class of non-nucleoside antiviral drugs

emission=576 measured in MeOH ϵ=9

7-bis(dimethylamino)-3

Zosuquidar trihydrochloride - CAS# 167465-36-3 Size:Solid 2 mg ARRY-520 had low nanomolar antiproliferativeZosuquidar, also known as LY 335979, is a potent P glycoprotein (P gp) inhibitor, which binds with high affinity to P glycoprotein and inhibits P glycoprotein mediated multidrug resistance (MDR). P glycoprotein, encoded by the MDR 1 gene, is a member of the ATP binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product derived cytotoxic agents. Product information CAS Number: 167465