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DZ2002 ocysteine (SAH) 8-hexahydroquinoline-3-carboxylate

SKU: 75298680866

4.4
SEK154.70 SEK204.70

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DZ2002 ocysteine (SAH) 8-hexahydroquinoline-3-carboxylateDZ 2002 is a potent reversible inhibitor of S adenosyl L homocysteine hydrolase (SAHH). DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models. DZ2002 prevents the development of experimental dermal fibrosis by reversing the profibrotic phenotype of various cell types and would be a potential drug for the treatment of systemic sclerosis. Product information CAS Number: 33231 14 0 Molecular Weight: 251. 24

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Description

8-hexahydroquinoline-3-carboxylate

Administration of GKT137831 throughout the 72-hour period of normoxia or hypoxia exposure attenuates HPASMC proliferation under normoxic conditions at the 20 μM concentration but had no effect on proliferation in normoxic HPAECs

J Cell Biol

BLT-1 (50 μM

is a diaminopyrimidine compound that induces the differentiation of MHC- (myosin heavy chain) positive cardiomyocytes from embryonic stem cells with an EC50 value of 0

DZ2002 ocysteine (SAH) 8-hexahydroquinoline-3-carboxylateDZ 2002 is a potent reversible inhibitor of S adenosyl L homocysteine hydrolase (SAHH). DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models. DZ2002 prevents the development of experimental dermal fibrosis by reversing the profibrotic phenotype of various cell types and would be a potential drug for the treatment of systemic sclerosis. Product information CAS Number: 33231 14 0 Molecular Weight: 251. 24

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