Mirtazapine tespib ) demonstrates anti-tumor activity in

) demonstrates anti-tumor activity in human EGFR-L858R and EGFR-L858R-T790M expressing transgenic mice

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and neurotransmitters

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Mirtazapine tespib ) demonstrates anti-tumor activity inMirtazapine is an atypical antidepressant with noradrenergic and specific serotonergic activity. It works by blocking the 2 adrenergic auto and heteroreceptors (enhancing serotonin release), and selectively antagonizing the 5 HT2 and 5 HT3 serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5 HT1 receptor and blocks the histaminergic (H1) and muscarinic receptors. Mirtazapine is not a