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Zibotentan (ZD4054) pristin 5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]phenyl)phenoxy]butoxy]acetamido)-3

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Zibotentan (ZD4054) pristin 5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]phenyl)phenoxy]butoxy]acetamido)-3An orally available selective antagonist of the endothelin A (ET A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET A receptor, thereby inhibiting endothelin mediated mechanisms that promote tumor cell proliferation. Product information CAS Number: 186497 07 4 Molecular Weight: 424. 43 Formula: C19H16N6O4S Chemical Name: 2 (4 (1, 3, 4 oxadiazol 2 yl)phenyl) N (3 methoxy 5 methylpyrazin 2 yl)pyridine 3

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Description

5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]phenyl)phenoxy]butoxy]acetamido)-3

PubMed PMID: 25450597

InChiKey: HUFOZJXAKZVRNJ-UHFFFAOYSA-N

extracted from the roots of Polygonum cuspidatum Sieb

white blood count

Zibotentan (ZD4054) pristin 5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]phenyl)phenoxy]butoxy]acetamido)-3An orally available selective antagonist of the endothelin A (ET A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET A receptor, thereby inhibiting endothelin mediated mechanisms that promote tumor cell proliferation. Product information CAS Number: 186497 07 4 Molecular Weight: 424. 43 Formula: C19H16N6O4S Chemical Name: 2 (4 (1, 3, 4 oxadiazol 2 yl)phenyl) N (3 methoxy 5 methylpyrazin 2 yl)pyridine 3

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