TG100-115 zan (DMXAA) Nishikawa K

Nishikawa K

Defactinib (VS-6063) doses of 25 mg/kg twice a day or greater statistically significantly inhibits pFAK (Tyr397) at 3 hours

Epub 2014 Nov 21

Benclonidinum

Chemical Name: (2R)-2-[(2S)-4-[3-Chloro-5-fluoro-6-(2H-pyrazolo[3

TG100-115 zan (DMXAA) Nishikawa KTG100 115, inhibited PI3K and (IC50 values of 83 and 235 nM, respectively), whereas both PI3K and were relatively unaffected (IC50 values>1 M). As a gauge of general specificity, TG100 115 was also assayed against a 133 protein kinase panel, none of which was inhibited at IC50 values <1 M. Product information CAS Number: 677297 51 7 Molecular Weight: 346. 34 Formula: C18H14N6O2 Chemical Name: 3 [2, 4 diamino 6 (3 hydroxyphenyl)pteridin 7 yl]phenol