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TAK-700 8 antagonist Mitiglinide Calcium inhibits the Kir6

SKU: 50658981541

4.8
USD200.00 USD234.00

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TAK-700 8 antagonist Mitiglinide Calcium inhibits the Kir6TAK 700, is an orally bioavailable non steroidal androgen synthesis inhibitor of steroid 17alpha monooxygenase (17, 20 lyase) with potential antiandrogen activity. TAK 700 binds to and inhibits the steroid 17alpha monooxygenase in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen dependent growth signaling and may inhibit cell proliferation of androgen dependent tumor cells. Product information CAS

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Description

Mitiglinide Calcium inhibits the Kir6

105(1):136-144

58 μM on HCT116 cells

C=C1[C@H](CO)[C@@H](O)C[C@@H]1N1C=NC2C(=O)NC(N)=NC1=2

Epub 2012 Dec 4

TAK-700 8 antagonist Mitiglinide Calcium inhibits the Kir6TAK 700, is an orally bioavailable non steroidal androgen synthesis inhibitor of steroid 17alpha monooxygenase (17, 20 lyase) with potential antiandrogen activity. TAK 700 binds to and inhibits the steroid 17alpha monooxygenase in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen dependent growth signaling and may inhibit cell proliferation of androgen dependent tumor cells. Product information CAS

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