Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 the BET inhibitor CPI-0610 binds

the BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins

Smiles: OC(=O)CCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

laboratory

InChi: InChI=1S/C12H15N5O3

NC(N)=N/N=C/C1=CC(/C=N/N=C(N)N)=CC=C1

Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 the BET inhibitor CPI-0610 bindsEpirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.