PF-03716556 Size:10mg solid JW74 induces reduced cell growth

JW74 induces reduced cell growth in all three tested cell lines

water and DPPC bilayers

Formula: C12H12N2

Smiles: CC1=CN=C(NS(=O)(=O)C2=CC=CN=C2C2C=CC(=CC=2)C2=NN=CO2)C(=N1)OC

UNC0638 inhibits G9a HMTase with an IC50 ~15 nM and GLP

PF-03716556 Size:10mg solid JW74 induces reduced cell growthPF 03716556 is a potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease. PF 03716556 demonstrated 3 fold greater inhibitory activity than revaprazan. PF 03716556 did not display any species differences, exhibiting highly selective profile including the canine kidney Na(+), K(+) ATPase. Kinetics experiments revealed that PF 03716556 has a competitive and reversible mode of action. Product information CAS Number: