INK-128 Catalog No.:M10703-10 C1=NNC2=CC=CC=C21
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INK-128 Catalog No.:M10703-10 C1=NNC2=CC=CC=C21Sapanisertib, also known as TAK 228, MLN0128 and INK128, is a TORC1 2 inhibitor, is also an orally bioavailable inhibitor of raptor mTOR (TOR complex 1 or TORC1) and rictor mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. TORC1 2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some
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