Ciclesonide vestrol (aglycone) 5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

Smiles: CCOC(=O)NCCCC(=O)NCCC1C=CC=CC=1

is a small molecule inhibitor of polycomb repressive complex 1

VH298 represents a high-quality chemical probe of the HIF signalling cascade and an attractive starting point to the development of potential new therapeutics targeting hypoxia signalling

Lawrence JH

Ciclesonide vestrol (aglycone) 5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamideCiclesonide is an inhaled corticosteroids, used to ameliorate symptoms of airway inflammatory diseases, such as asthma, allergic rhinitis, and chronic obstructive pulmonary disease. Ciclesonide is a corticosteroid prodrug that is converted to its active form, desisobutyryl CIC. Des CIC is a glucocorticoid receptor agonist. Product information CAS Number: 126544 47 6 Molecular Weight: 540. 69 Formula: C32H44O7 Synonym: Alvesco Omnaris RPR251526