Epalrestat - CAS# 82159-09-9 752 Formula: C23H27ClN2O2

Formula: C23H27ClN2O2

SB203580 at higher concentrations activates the ERK pathway

Chemical Name: N-[4-({[4-(4-methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamide

Smiles: COC1=CC2CC[C@H]3[C@@H]4CC[C@H](NCCCCCCN5C(=O)C=CC5=O)[C@@]4(C)CC[C@@H]3C=2C=C1

As a prodrug

Epalrestat - CAS# 82159-09-9 752 Formula: C23H27ClN2O2Epalrestat is an aldose reductase inhibitor that is currently available for the treatment of diabetic neuropathy. In vivo, Epalrestat treatment significantly ameliorated the bleomycin mediated histological fibrosis alterations and blocked collagen deposition concomitantly with reversing bleomycin induced expression up regulation of TGF 1, AR, SMA and collagen I (both mRNA and protein). Product information CAS Number: 82159 09 9 Molecular Weight: 319.