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Pentoxifylline CS JNK 5a HCT-116 and MiaPaca cells

SKU: 11919962663

4.9
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Pentoxifylline CS JNK 5a HCT-116 and MiaPaca cellsPentoxifylline is a drug used to treat muscle pain in people with peripheral artery disease. Like other methylated xanthine derivatives, pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. It is being investigated for treatment of Alzheimer's disease. It is generic and sold under many brand names

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Description

HCT-116 and MiaPaca cells

6-di(H)methyl-1

PubMed Central PMCID: PMC5114414

CAS Number: 2204290-85-5

3-d]pyrimidin-2-yl}amino)pyridin-3-yl]piperazin-1-yl}methyl)-1H-1

Pentoxifylline CS JNK 5a HCT-116 and MiaPaca cellsPentoxifylline is a drug used to treat muscle pain in people with peripheral artery disease. Like other methylated xanthine derivatives, pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. It is being investigated for treatment of Alzheimer's disease. It is generic and sold under many brand names

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