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GK921 Catalog No.:M8587-2 Molecular Weight: 460

GK921 Catalog No.:M8587-2 Molecular Weight: 460

Name: GK921 Catalog No.:M8587-2 Molecular Weight: 460
Brand: trulybuild.in
SKU: 10754648785
Price: 124.95 USD
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SKU: 10754648785

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GK921 Catalog No.:M8587-2 Molecular Weight: 460GK921 is a transglutaminase 2 (TGase 2) inhibitor. GK921 showed cytotoxicity to RCC (average GI50 in eight RCC cell lines: 0. 905 M). A single treatment with GK921 almost completely reduced tumor growth by stabilizing p53 in the ACHN and CAKI 1 preclinical xenograft tumor models. TGase 2 inhibitor GK921 abrogates RCC growth in xenograft tumor models, suggesting the possibility of a new therapeutic approach to RCC. Product information CAS Number:

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Molecular Weight: 460

PubMed PMID: 25726556

PubMed PMID: 29047383

27-epoxypyrido[2

VH-298 is a potent VHL inhibitor that stabilizes HIF-α and elicits a hypoxic response via a different mechanism

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