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PKR Polyclonal Antibody, 50ul[BT-AP07244] Sampling Tubes A chromosomal translocation and gene

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PKR Polyclonal Antibody, 50ul[BT-AP07244] Sampling Tubes A chromosomal translocation and geneThe protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms

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Description

A chromosomal translocation and gene fusion between this gene and zinc finger| MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient

MAP kinases

on their outer cell wall

This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia

regulating cellular cholesterol homoeostasis

PKR Polyclonal Antibody, 50ul[BT-AP07244] Sampling Tubes A chromosomal translocation and geneThe protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms

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