Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma An important paralog of this

An important paralog of this gene is GK

The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex

inducing leukocyte migration and activation

The PIAS family contains a conserved RING domain that has been linked to a function as a small ubiquitin-related modifier (SUMO) ligase

The protein encoded by BAX belongs to the BCL2 protein family

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma An important paralog of thisMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.