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DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene are

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DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene arePPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B.

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Description

Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies

The cytokine encoded by CCL19 (C-C motif chemokine ligand 19) may play a role in normal lymphocyte recirculation and homing

Also found in the colon

NONO (non-POU domain containing

TAS2R8 product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily

DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene arePPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B.

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