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Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets and may also have a

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Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets and may also have aThe protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The

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Description

and may also have a role in controlling cell growth and/or differentiation

the biological significance of the two forms is not known

It functions as a receptor for endogenous ligands

Mutations in this gene cause Alexander disease

Alternatively spliced transcript variants encoding different isoforms have been found for HRH2

Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets and may also have aThe protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The

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