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Factor I Polyclonal Antibody, 100ul Cryogenic Vials and functions as a critical

SKU: 96523918408

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Factor I Polyclonal Antibody, 100ul Cryogenic Vials and functions as a criticalCFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an

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Description

and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms

and distribution of the membrane-associated alpha subunit in kidney and intestine

Also in fetal lung fibroblasts and fetal brain

Defects in this gene are a cause of macular corneal dystrophy (MCD)

14Z-eicosatetraenoic acid (5-OXO-ETE)

Factor I Polyclonal Antibody, 100ul Cryogenic Vials and functions as a criticalCFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an

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