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MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix consisting of KRTHB1

SKU: 96119748835

4.5
USD185.00 USD217.00

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MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix consisting of KRTHB1Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007

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Description

consisting of KRTHB1

transcription regulation

This gene encodes a member of the class-II aminoacyl-tRNA synthetase family

This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells

Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix consisting of KRTHB1Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007

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