YMEL1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Mutations in the gene are

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

and Th2 lymphocytes generated during allergic inflammation

This gene encodes a protein localized in mitochondria and closely related to paraplegin

The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis

which is produced by the pancreatic acinar cells

YMEL1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Mutations in the gene areThe protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.