HtrA2(Phospho Ser212) Polyclonal Antibody, 100ul Serum & Sample Tubes Contains 2 CHORD domains

Contains 2 CHORD domains

May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2

This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors

and expresses two proteins: a shorter

HtrA2(Phospho Ser212) Polyclonal Antibody, 100ul Serum & Sample Tubes Contains 2 CHORD domainsThis gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear localization of this