AOAH Polyclonal Antibody, 50ul Gene Editing Vaults are multi-subunit ribonucleoprotein structures

Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport

This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1

It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family

It contains a single doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization

and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome

AOAH Polyclonal Antibody, 50ul Gene Editing Vaults are multi-subunit ribonucleoprotein structuresThis locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram negative bacteria. Alternatively spliced transcript variants have been described.