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DOCK 2 Polyclonal Antibody, 100ul Cell Dissociation This gene is one of

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DOCK 2 Polyclonal Antibody, 100ul Cell Dissociation This gene is one ofDedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long term survival

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Description

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17

they associate with the three catenins

Malonyl-CoA is an intermediate in fatty acid biosynthesis| and also inhibits the transport of fatty acyl CoAs into mitochondria

May also mediate the transport of inorganic phosphate

Also involved in negative regulation of the cell cycle

DOCK 2 Polyclonal Antibody, 100ul Cell Dissociation This gene is one ofDedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long term survival

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