WDR33 Rabbit Polyclonal Antibody, 50ul Protein Post-translational Modification Mutations in this gene result

Mutations in this gene result in one form of autosomal dominant hearing impairment

The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1

The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia

Several transcript variants encoding different isoforms have been found for BCOR

some of which encode the same protein

WDR33 Rabbit Polyclonal Antibody, 50ul Protein Post-translational Modification Mutations in this gene resultThis gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly his and trp asp (GH WD) which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression signal transduction apoptosis and gene regulation. This gene is highly expressed in