TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation The receptor functions as a

The receptor functions as a neurotransmitter-gated ion channel

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules

namely the Shaw subfamily

growth control

which regulates its nuclear matrix and chromatin association

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation The receptor functions as aCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only