Beclin-1(Phospho-Ser93) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection Mutations in this gene are

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

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Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q

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concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida

Beclin-1(Phospho-Ser93) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection Mutations in this gene areThis gene encodes a protein that regulates autophagy a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes including tumorigenesis neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.