UHRF1 Polyclonal Antibody, 100ul Filtration This antibody is specific to
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UHRF1 Polyclonal Antibody, 100ul Filtration This antibody is specific toUHRF1 encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. E3 ubiquitin protein ligase UHRF1binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent
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