NF-YC Polyclonal Antibody, 100ul Sealing Film It is an intergral membrane

It is an intergral membrane protein that is highly expressed in fetus

Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion

Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome

The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells

and is therefore a potential candidate gene for this disorder

NF-YC Polyclonal Antibody, 100ul Sealing Film It is an intergral membraneNFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone like motif. Multiple transcript variants