SOD2 Polyclonal Antibody, 100ul[BT-AP14365] Liquid Handling Low level of expression seen

Low level of expression seen in the liver| thymus| and peripheral blood leukocytes

This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34

Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined

subcellular location:Colocalizes with actin

Pseudogenes of this gene have been identified on chromosome 5

SOD2 Polyclonal Antibody, 100ul[BT-AP14365] Liquid Handling Low level of expression seenThis gene is a member of the iron manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.