TIP60(Phospho Ser86) Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) SURF1 encodes surfeit locus protein

SURF1 encodes surfeit locus protein 1 localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex

The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box| that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA)

Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs)

Alternatively spliced transcript variants encoding multiple isoforms have been observed for ARHGAP12

The type II isozyme

TIP60(Phospho Ser86) Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) SURF1 encodes surfeit locus proteinThe protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV 1 TAT interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal