UBP6 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Three alternatively spliced transcript variants

Three alternatively spliced transcript variants for this gene have been described

This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon

both domains are DNA-binding motifs

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains

Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism

UBP6 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Three alternatively spliced transcript variantsCatalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,disease: Involved in tumorigenesis.,Has an ATP independent isopeptidase activity, cleaving at the C terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous: The USP6 gene only exists in the primate lineage.,Belongs to the peptidase C19 family.,Contains 1 Rab GAP TBC domain.,tissue specificity: Testis