VWF Polyclonal Antibody, 100ul Cryopreservation The paired box 4 gene

The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells

Eukaryotes contain two protein translational systems

Three transcript variants encoding different isoforms have been identified for CA12

Constitutive activation of this gene caused either by somatic mutations

Weakly expressed in pancreas

VWF Polyclonal Antibody, 100ul Cryopreservation The paired box 4 geneThis gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.