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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome Our adenoviral packaging system can

SKU: 8629849577

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome Our adenoviral packaging system canPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

Our adenoviral packaging system can accommodate large gene fragments and ensures high-level expression of target genes

An alternatively spliced transcript variant of this gene has been reported| however| its full length nature is not known

resides in the critical region for VCFS/DGS on 22q11

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation

This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome Our adenoviral packaging system canPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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