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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome suggesting a role for this

SKU: 84113758807

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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome suggesting a role for thisERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells

The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin

This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias

which are important regulators of hematopoiesis and cardiogenesis in mammals

The N-end rule pathway is one proteolytic pathway of the ubiquitin system

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome suggesting a role for thisERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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