ZFY27 Rabbit Polyclonal Antibody, 50ul Supplements Defects in TRPS1 are a

Defects in TRPS1 are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III

The full-length protein undergoes self-cleavage to produce shorter

A change in expression of this protein has been noted in pancreatic cancer-derived cells

EID-1 gives a specific tag for transcriptional activation

Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms

ZFY27 Rabbit Polyclonal Antibody, 50ul Supplements Defects in TRPS1 are aThis gene encodes a protein with several transmembrane domains a Rab11 binding domain and a lipid binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia however the pathogenicity of the mutation which may simply represent a polymorphism is unclear.