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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance which may play a role

SKU: 82381542017

4.6
USD185.00 USD231.00

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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance which may play a roleFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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Description

which may play a role in the signal transduction pathway mediated by multiple Wnt proteins

In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation

The protein encoded by this gene is a core subunit of the elongator complex

This protein has been found to bind to p47phox

The protein that coordinates these activities is the basal transcription factor TFIID

FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance which may play a roleFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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