MLK4 Polyclonal Antibody, 100ul Drying & Desiccation a member of the histidine

a member of the histidine triad gene family

This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex| tramtrack| bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs

Mutations in this gene may be associated with hereditary nonpolyposis colon cancer

It also interacts with multiple intracellular calcium release channels| and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor

Among its related pathways are LKB1 signaling events

MLK4 Polyclonal Antibody, 100ul Drying & Desiccation a member of the histidineMLK4 is a Protein Coding gene. Mitogen activated protein kinase kinase kinase MLK4 is a negative regulator of TLR4 signaling. Does not activate JNK1 MAPK8 pathway, p38 MAPK14, nor ERK2 MAPK1 pathways. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is KSR1.