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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments subunit:Interacts with MKL1 and SRF

SKU: 82028813953

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Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments subunit:Interacts with MKL1 and SRFThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

subunit:Interacts with MKL1 and SRF

The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains

Reduces all-trans-retinal and 9-cis retinal

has been identified as a novel SNF1-related serine/threonine kinase

This protein is involved in cell adhesion

Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments subunit:Interacts with MKL1 and SRFThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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