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GAAP Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) disease:A chromosomal aberration involving FOXO4

SKU: 8180800348

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GAAP Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) disease:A chromosomal aberration involving FOXO4TMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4) is a Protein Coding gene. Diseases associated with TMBIM4 include lassa fever and venezuelan hemorrhagic fever. An important paralog of this gene is FAIM2. Anti apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5 trisphosphate (IP3) mediated Ca2+ release.

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Description

disease:A chromosomal aberration involving FOXO4 is found in acute leukemias

This gene encodes a protein that contains the GAP-related domain (GRD)| a characteristic domain of GTPase-activating proteins (GAPs)

through calcium-independent cell-adhesion activity

Mutations in this gene result in Dystonia 3

Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described

GAAP Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) disease:A chromosomal aberration involving FOXO4TMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4) is a Protein Coding gene. Diseases associated with TMBIM4 include lassa fever and venezuelan hemorrhagic fever. An important paralog of this gene is FAIM2. Anti apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5 trisphosphate (IP3) mediated Ca2+ release.

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