8ODP Polyclonal Antibody, 20ul Apoptosis & Autophagy DEAH-box helicase 8 contains the

DEAH-box helicase 8 contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins

These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation

It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA

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Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response

8ODP Polyclonal Antibody, 20ul Apoptosis & Autophagy DEAH-box helicase 8 contains theMisincorporation of oxidized nucleoside triphosphates into DNA RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates such as 8 oxo dGTP 8 oxo dATP 2 hydroxy dATP and 2 hydroxy rATP to monophosphates thereby preventing misincorporation. The encoded protein is localized mainly in the