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GTR2 Polyclonal Antibody, 50ul Molecular Biologyn The protein encoded by this

SKU: 81597540016

4.6
PLN162.00 PLN210.00

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GTR2 Polyclonal Antibody, 50ul Molecular Biologyn The protein encoded by thisThis gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi Bickel syndrome and noninsulin dependent diabetes mellitus (NIDDM). Alternative

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Description

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG)

prolonging the half-life of IGFs and altering their interaction with cell surface receptors

Contains 2 LRR (leucine-rich) repeats

Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA)

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

GTR2 Polyclonal Antibody, 50ul Molecular Biologyn The protein encoded by thisThis gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi Bickel syndrome and noninsulin dependent diabetes mellitus (NIDDM). Alternative

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