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1A68 Rabbit Polyclonal Antibody, 50ul Adenovirus Packaging The activity of this ubiquitin

SKU: 81075570164

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SEK185.00 SEK218.00

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1A68 Rabbit Polyclonal Antibody, 50ul Adenovirus Packaging The activity of this ubiquitinHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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Description

The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis

Migrates to the nucleus when complexed with SMAD4

which includes type 2 integral membrane metallopeptidases

Two alternately spliced transcripts encoding two protein isoforms have been identified

in the same transcriptional orientation

1A68 Rabbit Polyclonal Antibody, 50ul Adenovirus Packaging The activity of this ubiquitinHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon

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